Zoloft

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Zoloft® (sertraline) is a prescription antidepressant in a class known as selective serotonin reuptake inhibitors (SSRIs). SSRIs work by increasing the amount of serotonin in the brain. Zoloft® is approved by the FDA for the treatment of major depression, obsessive-compulsive disorder, panic attacks, posttraumatic stress disorder, social anxiety disorder, and premenstrual dysphoric disorder.[1]

Side effects of Zoloft® include dryness in the mouth, reduced appetite, nausea, sexual dysfunction, insomnia and diarrhea. In severe cases, Zoloft® can cause uncontrollable shaking and extreme mood changes including suicidal thoughts or tendencies. Suicide attempts or ideologies with Zoloft® are most common among patients under the age of 24.

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Zoloft-nv.jpg
Flickr: chris.corwin
Brand name for Sertraline[2]
Manufacturer Pfizer Inc.[2]
Generic available? Yes
Uses Major depressive disorder (MDD), obsessive-compulsive disorder (OCD), panic disorder, post-traumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), social anxiety disorder[3]
Common side effects Nausea, diarrhea, constipation, vomiting, dry mouth, gas or bloating, loss of appetite or weight changes, drowsiness, dizziness, excessive tiredness, nervousness, changes in sex drive or ability[1]
Major side effects Vision changes, seizures, fever, confusion, fast or irregular heartbeat, abnormal bleeding or bruising, hallucinations[1]
Warnings Patients who have recently had a heart attack, seizures or liver or heart disease, or who are allergic to latex (for oral solution) may be unable to take Zoloft®. Patients taking monoamine oxidase inhibitors (MAOI), pimozide (Orap), or disulfiram (Antabuse) cannot take Zoloft®. A small number of children, teenagers, and young adults experience suicidal thoughts while taking Zoloft®.[1]
Disclaimer The information provided by PharmacyDrugGuide.com is not a substitute for professional medical advice, diagnosis, or treatment. Do not take any action based on the information on this page without consulting a physician.
Author Selena Robinson
 
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Contents

Zoloft® Overview

Zoloft® is an antidepressant used to treat several different disorders:

  • Major depression, a mood disorder in which feelings like sadness or loss interfere with everyday life for a long period of time.[1]
  • Obsessive-compulsive disorder, characterized by troublesome thoughts that persist, and the need to repeat specific actions.[1]
  • Panic disorder, in which patients experience recurrent panic attacks and may or may not suffer from agoraphobia, a fear of settings like crowds, bridges and the outdoors.[1]
  • Posttraumatic stress disorder, a condition developed after a particularly traumatic or frightening event that may involve actual or threatened death or serious injury.[1] [4]
  • Social anxiety, an extreme fear of interacting with other people that hinders normal life.[1] [4]
  • Premenstrual dysphoric disorder, which includes mood swings, irritability, bloating, and breast tenderness.[2] [3]

Zoloft® Abuse

Zoloft® is not a controlled substance and it is not commonly abused. While therapeutic doses do result in positive mood changes, large doses or doses taken by alternate methods do not seem to produce a desired effect. Zoloft® overdose may result in somnolence (drowsiness), vomiting, fast heart rate, nausea, dizziness, agitation, tremor, and death.[4]

Zoloft® Side Effects

Zoloft® has a number of common side effects. These may include:

  • Nausea or vomiting
  • Diarrhea
  • Constipation
  • Gas or bloating
  • Loss of appetite or weight changes
  • Drowsiness or excessive tiredness
  • Dizziness
  • Nervousness
  • Headache
  • Pain, burning, or tingling in the hands or feet
  • Changes in sex drive or ability
  • Excessive sweating[1]

Major side effects of Zoloft® are rare, but may require medical assistance:

  • Rash
  • Hives
  • Itching
  • Swelling of the face, throat, or tongue
  • Difficulty breathing
  • Vision changes
  • Seizures
  • Fever
  • Confusion
  • Fast or irregular heartbeat
  • Severe muscle stiffness
  • Hallucinations
  • Abnormal bleeding or bruising[1]
  • Zoloft® can cause complications if used in the final stages of pregnancy.[1]
  • Due to the possibility of drowsiness, Zoloft® patients are cautioned against operating a motor vehicle until it is clearly safe to do so on the medication.[1]

Prescription Drugs

Information on prescription drugs like Zoloft
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Also See: Zoloft Side Effects, Zoloft Patient Assistance Programs, Zoloft and Pregnancy, Zoloft Free Samples, Sertraline Coupons, Lexapro, Marijuana and Prozac, Viibryd

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References

  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 http://www.ncbi.nlm.nih.gov/pubmedhealth/PMHT0012108/?report=details
  2. 2.0 2.1 2.2 http://www.zoloft.com/
  3. 3.0 3.1 http://www.zoloft.com/about-zoloft.aspx
  4. 4.0 4.1 4.2 http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=52077